Pamela Shaw

Professor Dame Pamela Shaw is an internationally renowned clinician and academic researcher known for her work in the field of ALS/MND. Pamela is a Consultant Neurologist at the Sheffield Teaching Hospitals NHS Foundation Trust and Professor of Neurology and Director of the Sheffield Institute of Translational Neuroscience (SITraN), where the academic research underpinning Crucible’s therapeutic candidate was developed. The range of Pamela’s molecular, genetic and clinical contributions has attracted international recognition and the award of multiple prizes, including a Wellcome Trust Senior Fellowship in Clinical Science and an NIHR Senior Investigator award. In 2014, she was made a Dame Commander of the Order of the British Empire (DBE) and, in 2022 she received the British Neuroscience Association award for an outstanding contribution to neuroscience. Her translational research had led to several improved outcomes for patients with MND.