NEWS

Crucible Therapeutics announces the appointment of Dr Cliff Holloway as Chief Executive Officer

Crucible Therapeutics, a biopharmaceutical company developing novel therapies for amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases, today announced the appointment of Dr Cliff Holloway as Chief Executive Officer. Dr Holloway will also join the company’s Board of Directors.

“I am very pleased to welcome Cliff Holloway as our new CEO,” said Neill Moray Mackenzie, Executive Chairman of the Board and Entrepreneur-in-Residence at Argobio Studios. “Cliff brings extensive leadership experience from across the biotech and healthcare sectors and an impressive record of execution and value creation. His expertise and vision make him an ideal leader to guide Crucible into its next phase of growth.”

Commenting on his appointment, Dr Holloway said:

“I’m thrilled to have the opportunity to lead Crucible and advance our programs towards delivering transformative therapies for patients with serious neurodegenerative diseases. I have a very personal mission to ensure Crucible’s success following the ALS diagnosis and passing of a very good friend and colleague just last year. Crucible’s novel RNA therapeutics represents an innovative approach to treating these devastating conditions and offers these patients much more than just hope. I look forward to working with our talented team and our world-class partners at the Sheffield Institute for Translational Neuroscience to drive our programs forward into the clinic and beyond.”

About Dr Cliff Holloway

Dr Cliff Holloway is an experienced biotechnology executive with over two decades of leadership in the sector. He was a former CEO, CBO and Director for several public and private biotechnology companies including Ethris GmbH, Scancell Holdings (AIM:SCLP), Benitec Biopharma, Biosceptre International, Immune Sytem Therapeutics, and Arana Therapeutics.

He has specialised in facilitating the growth, organisation, and culture of companies transitioning from the laboratory to the clinic by guiding teams through major clinical, regulatory, and development milestones. He has broad therapeutic development experience in a range of drug classes and modalities, with extensive experience in partnering of such assets from preclinical to clinical stage, including asset acquisition, in/out-licensing, and co-development. He has raised over £100m from private, strategic and institutional investors and established a strong global network within the investor/advisor, pharma and biotech communities.

Dr Holloway holds a PhD in Medicinal Chemistry and a Bachelor of Pharmacy from the University of Nottingham, UK.